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價格 | ¥4800.00 |
品牌 | NewEast Biosciences |
產(chǎn)地 | 中國 武漢 |
貨號 | 26234 |
規(guī)格 | 100ul |
說明書 | 說明書下載 |
PIK3CA(E542K) [26234]
[100ul]
Catalog Number: 26234 |
Gene Symbol: PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha |
Description: Anti PIK3CA(E542K) Mouse Monoclonal Antibody |
Background: Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer. |
Immunogen: A synthetic peptide from the internal region of PIK3CA which includes the mutation of E542K, human origin. |
Applications: ELISA, WB |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:2000 |
Concentration: 1 mg/ml |
Host: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: |
Purity: Purified from ascites |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes E542K mutant, but not wild-type PIK3CA of vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Western blot: |
Western blot analysis of recombinant PIK3CA(E542K) and wildtype proteins. Purified His-tagged PIK3CA(E542K) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti PIK3CA(E542K) monoclonal antibody (Cat. #26234). |
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